Sex and gender equitable research
Sex and gender differences are often overlooked in research design, study implementation and scientific reporting, as well as in scientific communication in general. This omission limits the possibility to generalize research findings and their applicability to clinical practice, particularly for women but also for men. This section deals with this topic.
Sex and Gender in research involving humans according to the Human Research Act (HRA): Issues to consider.
This document reflects the swissethics recommendations on sex and gender in research involving humans according to the HRA.
Sex and Gender in research involving humans according to the Human Research Act: Recommendation for the ethical review of research projects.
Weblinks on the subject:
Improving sex and gender equity in research protocols: the new SAGER-swissethics recommendations, A. Gayet-Ageron et al. Swiss Med Wkly. 2024;154:4051, DOI: 10.57187/s.4051. Link
ICH Considerations: Sex-related Considerations in the Conduct of Clinical Trials, June 2009
European Institute of Women's Health: Sex and Gender Policy Briefs
Federal Office of Public Health FOPH: Research on Health Equity
US National Institutes of Health - Office of Research on Women's (ORWH): NIH Inclusion Outreach Toolkit
GENDRO: Link
The SAGER Guidelines (Sex and Gender Equity in Research): Link to the guidelines
Webinar elucidating the importance of WHO's adoption of the SAGER guidelines, accompanied by a panel discussion expertly moderated by Dr. Richard Horton, Editor-in-Chief of The Lancet. Link
European Federation of Pharmaceutical Industries and Associations (EFPIA): Right from the start - Including more women in Clinical Trials. Link
CIOMS-GENDRO Meeting report February 2023: Sex and gender considerations in research: the role of research ethics guidelines and research ethics committees. Link
Why Diverse Clinical Trial Participation Matters, A.L Schwartz, N Engl J Med 2023; 388:1252-1254, DOI: 10.1056/NEJMp2215609. Link
Sex and gender in science: How to navigate a challenging are of reseach to the benefit of all, Nature, 2024, Link